Non-variceal upper gastrointestinal bleed as first presentation of primary systemic amyloidosis – A case report

Abstract

Gastrointestinal (GI) tract manifestations of amyloid deposition include diarrhea, GI hemorrhage, steatorrhea, or constipation. Here, we report an elderly female presenting with GI hemorrhage due to gastric ulceration and 4–6 polypoidal lesions with intermittent ooze in the duodenum as a first presentation of primary systemic amyloidosis. The bleed was managed with proton-pump inhibitors and hemospray application. She received chemotherapy for multiple myeloma after stabilization. A high index of suspicion is needed to diagnose amyloidosis causing GI hemorrhage.

Keywords:

Gastrointestinal amyloidosis Gastrointestinal hemorrhage Hemospray
Udgirkar, S., Jain, S., Chandnani, S. ., Rathi, P. M. ., Contractor, Q. ., & Kamat, R. . (2021). Non-variceal upper gastrointestinal bleed as first presentation of primary systemic amyloidosis – A case report. International Journal of Health Sciences, 15(4), 50–52. Retrieved from https://ijhs.qu.edu.sa/index.php/journal/article/view/4625
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