Original Articles

Manuscript must be in good English, typewritten using Times New Roman font size 12 only, double-spaced with one inch margin on all sides.

All manuscripts must be accompanied by a certificate signed by the corresponding author and all coauthors that they have seen and approved the final version of the manuscript and that the article has NOT been published or submitted to any other journal for publication. The corresponding author is responsible for obtaining permission from the copyright owner for the use of any copyrighted material in the submitted article.


Each original article must contain:

1. Title page

Title page should contain the following information:

  1. Complete title of the article
  2. Name(s) of author(s)
  3. Department(s)
  4. Institution(s) at which work was performed
  5. Official phone/fax no, mobile phone no, personal e-mail address of the corresponding author, and institutions address.


2. Structured Abstract

Abstract should be factual condensation of the entire work and should NOT exceed 250 words and must be written under the following subheadings:

  1. Objectives
  2. Methodology
  3. Results
  4. Conclusion


3. Text

Text must be arranged under the following headings:

  1. Introduction
  2. Methods
  3. Results
  4. Discussion
  5. Conclusion(s)
  6. Ethics approval and consent to participate
  7. Availability of data and material (Details -
  8. Competing interests
  9. Funding Statement
  10. Authors’ contributions
  11. Acknowledgements (if any)
  12. ORCID link of the corresponding author (


If any of the sections are NOT relevant to your article, please write 'Not applicable'.

Introduction provides a brief survey of literature, purpose of the study, etc.; the Methodology and procedures should be concise but detailed enough to enable the reader to reproduce the experiment. Commonly used procedures and methods need not be described but require a reference to the original source. In Result Section only findings, presented in the form of tables or figures, should be included without duplication of presentation and no discussion of the significance of the data. Discussion should present the significance of the data under the prevalent understanding of the phenomenon. Speculative discussion is allowed but it should be concise and corroborated by the presented data. Conclusion summarizes the study and is drawn from the results and discussion. Acknowledgements, if any, should be placed at the end of the text and before references.


4. References

References should be listed consecutively as NUMERICAL in PARENTHESES. The final bibliography should be in the order in which they are quoted in the text and written in Vancouver Style as mentioned below:

(i). Standard journal article.

Rasheed Z, Haqqi TM. Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes. Biochim Biophys Acta. 2012;1823:2179-89.


For seven or more authors, list only first six and add et al as mentioned below:

Rasheed N, Ahmad A, Singh N, Singh P, Mishra V, Banu N, et al. Differential response of A 68930 and sulpiride in stress-induced gastric ulcers in rats. Eur J Pharmacol. 2010;643:121-8.


(ii). Chapter in a book.

Rasheed Z, Haqqi TM. Cytokine networks and MAPKs “ towards new therapeutic targets for rheumatoid arthritis. In: Preedy VR, Hunter R, eds. Cytokine Modern insights into disease from molecules to man. Enfield, Science 2011; 31-47.


5. Tables and Figures (or Images)

Tables and figures, complete with legends and footnotes, should be on separate pages. The tables and figures pages should be consecutively numbered. Position of the tables or figures in the text must be indicated.


Instructions for Preparation of Images:

Please note: An image can refer to the following: Graphs, photographs, maps, charts, paintings, drawings, diagrams, etc.

Images must be embedded within the manuscript text of the article. Once the article accepted for publication, the author may be asked for an image in high resolution file format.

It is strongly recommended before embedding images in the manuscript, images must be prepared as mentioned below in the image specifications section.


Image specifications

Images must be prepared in accordance with the instructions mentioned on the PubMed Central website:

The key factor for preparation of images for sufficient quality is images must have a minimum resolution of 300 dots per inch (dpi) for the grayscale (or black and white) and at least 600 dpi for color scale. The acceptable image formats are tiff, jpeg, gif, psd or png.


Image Copyright

For any image that the authors have not made themselves, the authors will need to have written permission to reproduce that image, even if the image is posted on the internet. It is the authors responsibility to obtain permission to use the images, not the publishers. Permission must be obtained in writing before the article can be submitted.

For complete information, please visit the Copyright Agency Limited website:



 Systematic Reviews or Meta-Analysis should be systematic, critical assessments of literature and data sources pertaining to clinical or basic sciences topics that includes a statistical technique for quantitatively combining the results of multiple studies that measure the same outcome into a single pooled investigation. Data must be searched for and selected systematically for inclusion and critically evaluated, and the search and selection process must be mentioned. The text should NOT exceed 6000 words excluding abstract, references, tables and figures.


Each of the sections of these articles should include specific sub-sections as follows:

 Structured Abstract: (Not exceed 250 words):

  1. Objectives 
  2. Methodology
  3. Results
  4. Conclusion



  1. Rationale
  2. Objectives
  3. Research question



  1. Study design
  2. Participants, interventions, comparators
  3. Systematic review protocol
  4. Search strategy
  5. Data sources, studies sections and data extraction
  6. Data analysis



  1. Provide a flow diagram of the studies retrieved for the review
  2. Study selection and characteristics
  3. Synthesized findings
  4. Risk of bias



  1. Summary of main findings
  2. Limitations
  3. Conclusions


Declaration Statements:

  1. Competing interests
  2. Funding Statement
  3. Authors’ contributions
  4. Acknowledgements (if any)
  5. ORCID link of the corresponding author (


If any of the sections are NOT relevant to your article, please write 'Not applicable'. For all other information’s including title page, declaration statements, typing and reference style, please follow the original articles instructions.



The case report/series will only be considered if they represent unique first time or rarest-of-the-rare observations and should have clinical significance, new adverse effect(s) of a drug or other unique observations, etc. Patient consent for publication must be obtained from the patient in written or, if this is not possible, the next of kin before submission. The author(s) must have been involved in the care of the patient.

Case Report /case series should contain a single paragraph abstract and text should not exceed 1000 words (excluding abstract, references, tables and figures) with maximum 10 bibliographic references and either three figures or three tables. Each case report must contain:

  1. Summary (should not exceed 120 words)
  2. Introduction
  3. Case Presentation
  4. Discussion
  5. Conclusion
  6. Patient consent
  7. Availability of data and material (Details -
  8. Competing interests
  9. Funding Statement
  10. Authors’ contributions
  11. Acknowledgements (if any)
  12. ORCID link of the corresponding author (


If any of the sections are NOT relevant to your article, please write 'Not applicable'.

Authors must describe how the case report is unique, rarest-of-the-rare or unusual as well as its educational and/or scientific merits in the covering letter that accompanies the submission of the manuscript.

For all other information including title page, typing and reference style, please follow the instructions for original articles.



Rapid/Special/Short communication should be complete work, such as complete results of a short pilot study, not merely a preliminary report and should not exceed 1500 words with one figure and/or one table. An editorial decision will be provided rapidly without reviews. For writing and references style, follow the same instructions listed above.



Opinions on topics and articles recently published in the journal will be considered for publication if they are objective and constructive in nature and provide some academic or clinical interest to the readers. These letters may also be forwarded to the author of the cited article for possible response. The editor reserves the right to shorten these letters, delete objectionable comments, make other changes, or take any other suitable decision to comply with the style and policies of the journal. For writing and references style, follow the same instructions listed above.



Editorial will be written either by a member of the editorial board or someone invited by the editor as solicited by the Editor-in-Chief. It should have fewer than 1200 words or so WITHOUT abstract, no figures or tables. Editorials are generally concise scientific review on one or two of the hot topics pertaining to medical sciences. It may also be an opinion-based that discusses the key findings of research article(s) and places it in a broader context within the field. For writing and references style, follow the same instructions listed above.